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BiO-dOSimetric Tools for triagE to Responders

BiO-dOSimetric Tools for triagE to Responders (BOOSTER)

Funded under 7th FWP (Seventh Framework Programme)

Research area: SEC-2009-4.3-02 Bio-dosimetric tools to manage radiological casualties

Coordinator
Contact Person: NICOLAS Brigitte
Tel: +33-169082119
Fax: +33-169089528
Organisation:COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

RUE LEBLANC
PARIS 15
FRANCE

Project description
The effective management of an incident involving exposure of large numbers of people to radioactive material, whether accidental or following malevolent use of radioactivity, requires a mechanism for rapid triage of exposed persons.

The BOOSTER project addresses this requirement under Security Topic SEC-2009-4.3.2 Bio-dosimetric tools to manage radiological casualties. Current biodosimetric approaches frequently involve cytogenetics. The analysis of dicentric/ ring chromosomes is the mechanism of choice for precise estimation of an individual s exposure. Current optimisation of such analyses involves the automation of various steps in the process. However, chromosome analyses are performed on the first mitosis post-exposure and thus a significant limiting factor remains a cell culture step (2 days) that is impossible to reduce.

New biodosimeters are required that may not bring the same precision as cytogenetic analysis but will permit triage in the first hours post-accident into three populations (i.e. to identify individuals that require no further intervention, those who require close follow-up and those who require hospitalisation). BOOSTER is a capability project designed to research and develop new bio-dosimetric tools in order to quickly evaluate the level of potential casualties, determine by appropriate sensors their consequences, allow an efficient triage of exposed people, integrate a useful and usable toolbox, train civil protection operators and define commercial exploitation potentialities.

The BOOSTER project will use an integrated approach to deliver new bio-dosimetric tools. We propose to optimise existing tools for assessment of a radiological situation and to develop novel biodosimetric procedures for estimation of radiation exposure in cells from patients. These approaches will be combined in a prognostic toolkit that will allow effective management of exposed persons presenting at triage.



Project details
Project Acronym: BOOSTER
Project Reference: 242361
Start Date: 2010-07-01
Duration: 36 months
Project Cost: 4.58 million euro
Contract Type: Collaborative project (generic)
End Date: 2013-06-30
Project Status: Execution
Project Funding: 3.28 million euro

Participants
IZOTOPKUTATO INTEZET - MAGYAR TUDOMANYOS AKADEMIA HUNGARY
ORSZAGOS ATOMENERGIA HIVATAL HUNGARY
CANBERRA FRANCE FRANCE
KARLSRUHER INSTITUT FUER TECHNOLOGIE GERMANY
NATIONAL UNIVERSITY OF IRELAND, GALWAY IRELAND
UNIVERSIDAD POLITECNICA DE VALENCIA SPAIN
 

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